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hAChE-IN-6

SKU: orb1942524

Description

hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor with an IC50 of 0.16 μM. It also inhibits human butyrylcholinesterase (hBuChE) and glycogen synthase kinase 3 beta (GSK3β), with IC50 values of 0.69 μM and 0.26 μM, respectively. Additionally, hAChE-IN-6 impedes the self-aggregation of tau protein and amyloid-beta 1-42 (Aβ1-42), making it useful for Alzheimer's disease (AD) research.

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Key Properties

TargetCholinesterase (ChE),Others,GSK-3

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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hAChE-IN-6 (orb1942524)

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