Mouse IL-38 Protein, His tag (Animal-Free)

SKU: orb3148448

Description

Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-κB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.

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Key Properties

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Storage & Handling

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Storage	Please store the whole kit at -20°C upon receipt ,and protect from light. The kit is valid for 17 months. Please refer to the table below Materials supplied and Storage conditions to store all the components.
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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