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PL-3994

SKU: orb1943321

Description

PL-3994, a natriuretic peptide receptor-A (NPR-A) agonist resistant to neutral endopeptidase, functions as a bronchodilator, eliciting a concentration-dependent relaxation of pre-contracted guinea-pig trachea, evidenced by an IC50 of 42.7 nM.

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Key Properties

CAS Number952295-80-6
MW1875.19
FormulaC82H127N27O20S2
SMILESC([C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H]2NC(=O)[C@H](CO)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCCC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CN=CN4)NC(=O)[C@@H](NC(CCCCCC)=O)CSSC2)[H])(=O)N5[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(N)=O)C5

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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PL-3994 (orb1943321)

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