RPL5 (C) Antibody, Rabbit Polyclonal

SKU: orb67036

Description

Rabbit polyclonal to RPL5.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large60S subunit. Together these subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. RPL5 is a component of the 60S subunit that belongs to the L18P familyof ribosomal proteins. RPL5 is located in the cytoplasm and binds 5S rRNA to form a stable complexcalled the 5S ribonucleoprotein particle NP), which is necessary for the transport of nonribosomeassociatedcytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. RPL5 interactsspecifically with the beta subunit of casein kinase II. Variable expression of RPL5 in colorectalcancers compared to adjacent normal tissues has been observed, although no correlation betweenthe level of expression and the severity of the disease has been found.

Images & Validation

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Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human, Mouse

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of human RPL5
Molecular Weight	34
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-RPL5 antibody,anti-60S ribosomal protein L5 antibody,anti-MSTP030 antibody,anti-ribosomal protein L5 antibody,anti-DBA6 antibody

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Western blot analysis of total cell extracts from human HepG2(Lane1) and mouse liver(Lane2) using RPL5 antibody

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UniProt

P46777

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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