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Val-Cit-PAB-DEA-Dxd

SKU: orb2564824

Description

Val-Cit-PAB-DEA-Dxd (compound 81) is a cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs). It incorporates the topoisomerase I inhibitor Dxd, enabling targeted cytotoxicity. This reagent is widely used in ADC research and development for both in vitro and in vivo preclinical studies.

Images & Validation

Key Properties

CAS Number2964543-53-9
MW1013.08
FormulaC50H61FN10O12
SMILESN(C(COC(N(CCN(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C1)=O)C)C)=O)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Val-Cit-PAB-DEA-Dxd (orb2564824)

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