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Description
Research Area
Images & Validation
−| Tested Applications | ICC, IF, IHC-P, WB |
|---|---|
| Dilution Range | IHC-P: 1: 100-600, WB: 1:500, ICC: 1:100 |
| Reactivity | Guinea pig, Human, Mouse, Porcine, Rat |
Key Properties
−| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide derived from human CD163. Please contact us for the exact immunogen sequence. The peptide is available as orb374759. |
| Target | CD163 |
| Molecular Weight | 125 kDa |
| Purity | Polyclonal antibodies are purified by peptide affinity chromatography |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | 10 mM PBS, 0.02% sodium azide |
| Concentration | - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−Technical Guidance
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Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.
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Protocol Information
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SP Dai, CC Yang, Y Chin, WH Sun TDAG8-mediated distinct signaling pathways modulate the early and late phases of neuropathic pain iScience, (2024)
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Ruizhuo Ning, Poornima Venkat, Michael Chopp, Alex Zacharek, Tao Yan, Xu Cui, Don Seyfried, Jieli Chen D-4F increases microRNA-124a and reduces neuroinflammation in diabetic stroke rats Oncotarget, 5, 0 (2017)
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Priscila J. Carneiro, Amanda L. Clevelario, Gisele A. Padilha, Johnatas D. Silva, Jamil Z. Kitoko, Priscilla C. Olsen, Vera L. Capelozzi, Patricia R. M. Rocco, Fernanda F. Cruz Bosutinib Therapy Ameliorates Lung Inflammation and Fibrosis in Experimental Silicosis Frontiers in Physiology, 8, 159 (2017)
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Mengxuan Li,Nan Che,Xingzhe Liu,Yanhua Xuan,Yu Jin Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages Biochemical Pharmacology, 217, 115838 (2023)
Melina Rafiey et al. Histone Deacetylase Inhibitor Combined with Rosiglitazone Improves Cognitive Function Via Microglial Polarization and Increased Mature/Pro-BDNF in Alzheimer’s Disease Adv Pharm Bull, 16(1), 157-165 (2026)
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Saba Ahangaran, Arash Pourgholaminejad, Rahim Nosrati, Parvin Babaei TLR4 inhibition attenuates facilitatory effects of JQ1 on learning & memory via polarization of microglia, and BDNF expression in Alzheimer's disease model Behav Brain Res, 499, 115919 (2026)
Applications
Reactivity
Chen-Roetling, Jing et al. Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin J Neurochem, 139, 586-595 (2016)
Jie Gong et al. Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer Food Sci Nutr, 13(12), e71341 (2025)
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Mertens, Barbara et al. Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice Oncotarget, 9, 21978-22000 (2018)
de Vries, M. R. et al. Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels J Intern Med, 285, 59-74 (2019)
Heindryckx, Femke et al. Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse model Eur J Gastroenterol Hepatol, 24, 1020-1032 (2012)
Koronyo, Yosef et al. Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease Brain, 138, 2399-2422 (2015)
Gibson, D. L. et al. Maternal exposure to fish oil primes offspring to harbor intestinal pathobionts associated with altered immune cell balance Gut Microbes, 6, 24-32 (2015)
Chia Chi Kung et al. CLARIX FLO Inhibits DRG Adhesion-Induced Neuropathic Pain Through the CD44–TRPV1 Signaling Pathway International Journal of Molecular Science, 27, 7 (2026)
Applications
Reactivity
Koronyo-Hamaoui, Maya et al. Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease Brain, 143, 336-358 (2020)















































