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Orelabrutinib

SKU: orb1309294

Description

Orelabrutinib (ICP-022) is a potent, orally bioavailable, and irreversible small molecule inhibitor targeting Bruton's tyrosine kinase (BTK). It is widely used in preclinical research for studying B-cell malignancies and autoimmune diseases, demonstrating efficacy in both in vitro cellular assays and in vivo animal models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number1655504-04-3
MW427.49
Purity99.54%
FormulaC26H25N3O3
SMILESNC(=O)c1ccc(nc1-c1ccc(Oc2ccccc2)cc1)C1CCN(CC1)C(=O)C=C
TargetBTK
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.68 mM);DMSO:55 mg/mL (128.66 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

lymphocytic leukemia, Orelabrutinib, inhibit, Inhibitor, ICP 022, ICP022, ICP-022, Malignancies, cell, chronic, antineoplastic, Bruton tyrosine kinase, Btk, BTK, small

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Key Properties

No computed properties available.

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Orelabrutinib (orb1309294)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 130.00
5 mg
$ 240.00
1 ml x 10 mM (in DMSO)
$ 270.00
10 mg
$ 380.00
25 mg
$ 590.00
50 mg
$ 800.00
100 mg
$ 1,040.00
500 mg
$ 2,030.00
DispatchUsually dispatched within 3-5 working days
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