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Featured
Description
Research Area
Cell Biology
Images & Validation
−| Tested Applications | FC, IF, IHC-Fr, IHC-P |
|---|---|
| Dilution Range | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg /test |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Bovine, Canine, Equine, Rabbit, Sheep |
Related Conjugates & Formulations
−Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthesised phosphopeptide derived from human mTOR around the phosphorylation site of Ser2448 TD(p-S)YS |
| Target | MTOR |
| Molecular Weight | 289 kDa |
| Purification | Affinity purified by Protein A |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; 2610315D21Rik; flat; MTOR_HUMAN; MTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin (mTOR); Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1; Tyrosine-protein kinase mTOR; 2.7.11.1; MTOR_MOUSE; Rapamycin target protein 1 (RAPT1); MTOR_RAT; mechanistic target of rapamycin kinase; FK506 binding protein 12-rapamycin associated protein 1; mechanistic target of rapamycin (serine/threonine kinase); FK506 binding protein 12-rapamycin associated protein 2; rapamycin target protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; rapamycin associated protein FRAP2; dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1); mammalian target of rapamycin; mTOR (phospho-S2448); p-mTOR; phospho-mTOR; mTOR (phospho-Ser2448)
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Quick Database Links
Gene Symbol
MTOR
UniProt
UniProt Details
− No UniProt data available
Protocol Information
IHC-P
Immunohistochemistry Paraffin
IHC-Fr
Immunohistochemistry Frozen
FC
Flow Cytometry
IF
Immunofluorescence
Qiu, Jingping et al. Distinct subgroup of the Ras family member 3 (DIRAS3) expression impairs metastasis and induces autophagy of gastric cancer cells in mice J Cancer Res Clin Oncol, 144, 1869-1886 (2018)






