Urocortin II, mouse

SKU: orb1981330

Description

Urocortin II, mouse, is a selective and potent endogenous peptide agonist for the type-2 corticotropin-releasing factor (CRF2) receptor, displaying K_i values of 0.66 nM for CRFR2 and >100 nM for CRFR1, signifying its high specificity. It engages CRF2 receptors through mechanisms dependent on cAMP/PKA and Ca2+/CaMKII. Additionally, Urocortin II, mouse is localized in specific regions of the central nervous system, influencing central neurons that process visceral sensory information and regulate autonomic functions.

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Key Properties

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CAS Number	330648-32-3
MW	4152.96
Formula	C₁₈₇H₃₂₀N₅₆O₅₀
Target	CRFR

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

CRFR

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