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Corza6

SKU: orb2942775

Description

Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW4704.29
FormulaC203H293N55O61S7
TargetReactive Oxygen Species,Proton pump

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Corza6 (orb2942775)

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