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Cubilin rabbit pAb Antibody

SKU: orb770490
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Description

Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia

Images & Validation

Tested ApplicationsIHC
Dilution rangeImmunohistochemistry: 1/100 - 1/300
ReactivityHuman, Mouse, Rat
Predicted ReactivityMouse, Rat

Key Properties

ClonalityPolyclonal
IsotypeIgG
ImmunogenSynthesized peptide derived from the N-terminal region of human Cubilin
Molecular WeightObserved Band: 400kD
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/PreservativesPBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration1 mg/ml
DisclaimerFor research use only

Alternative Names

Anti-CUBN antibody, anti-IFCR antibody, anti-Cubilin antibody, anti-460 kDa receptor antibody, anti-Intestinal intrinsic factor receptor antibody, anti-Intrinsic factor-cobalamin receptor antibody, anti-Intrinsic factor-vitamin B12 receptor antibody

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Cubilin rabbit pAb Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

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Protocol Information

IHC
Immunohistochemistry
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Cubilin rabbit pAb Antibody (orb770490)

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Available Sizes

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50 μl
$ 250.00
100 μl
$ 390.00
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