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Dactinomycin

SKU: orb3023229

Description

Dactinomycin D (Actinomycin IV) is an antibiotic and autophagy activator produced by Streptomyces bacteria fermentation, which inhibits transcription and replication by inserting into the DNA double helix, and can also promote p53 phosphorylation and accumulation through MDM2 overexpression, serving as a chemotherapy drug for cancer treatment.

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Key Properties

CAS Number50-76-0
MW1255.42
Purity99.70%
FormulaC62H86N12O16
SMILESC(N[C@@H]1C(=O)N[C@H](C(C)C)C(=O)N2[C@@](CCC2)(C(=O)N(C)CC(=O)N(C)[C@@H]([C@@H](C)C)C(=O)O[C@@H]1C)[H])(=O)C=3C=4C(OC=5C(N4)=C(C(N[C@@H]6C(=O)N[C@H](C(C)C)C(=O)N7[C@@](CCC7)(C(=O)N(C)CC(=O)N(C)[C@@H]([C@H](C)C)C(=O)O[C@@H]6C)[H])=O)C=CC5C)=C(C)C(=O)C3N
TargetAutophagy,Antibiotic,Apoptosis,DNA/RNA Synthesis

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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  • Actinomycin D [orb146196]

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    100 mg, 250 mg, 1 g
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Dactinomycin (orb3023229)

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1 mg
$ 70.00
5 mg
$ 100.00
10 mg
$ 150.00
25 mg
$ 270.00
50 mg
$ 420.00
100 mg
$ 640.00
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