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FALGPA TFA

SKU: orb1980079

Description

FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releasing the furanacryloyl group. This release is measurable through colorimetric detection between 324 and 345 nm, serving as an indicator of collagenase activity. Additionally, FALGPA facilitates the identification of inhibitors for C. histolyticum collagenase.

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Key Properties

MW476.52
FormulaC23H32N4O7.XCF3COOH
SMILESO=C(C=CC1=CC=CO1)N[C@@H](CC(C)C)C(NCC(N2[C@H](C(N[C@@H](C)C(O)=O)=O)CCC2)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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FALGPA TFA (orb1980079)

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