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IMR-1

SKU: orb1300399

Description

IMR-1

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number310456-65-6
MW353.41
Purity98.08%
FormulaC15H15NO5S2
SMILESCCOC(=O)COc1ccc(\C=C2\SC(=S)NC2=O)cc1OC
TargetGamma-secretase
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.66 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:60 mg/mL (169.77 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

Target IC50
Notch:6 μMol/L
Cell Research
ChIP assay o the HES1 promoter usin the indicated antibodies following treatment of OE33 and 786-0 cells with DAPT (15 μM), IMR-1 (25 μM), or Vehicle (DMSO) using GAPDH as loading control. (Only for Reference)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

inhibit, Notch, IMR1, IMR-1, IMR 1, Gammasecretase, Inhibitor

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Key Properties

No computed properties available.

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IMR-1 (orb1300399)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 70.00
10 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
25 mg
$ 150.00
50 mg
$ 230.00
100 mg
$ 350.00
200 mg
$ 490.00
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