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M4K2163 dihydrochloride

SKU: orb2283336

Description

M4K2163 dihydrochloride, a potent and selective activin receptor-like kinase-2 (ALK2) inhibitor that is permeable to the blood-brain barrier (BBB), has an IC50 of 19 nM. This compound is useful in diffuse intrinsic pontine glioma (DIPG) research.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2863635-04-3
MW480.4
FormulaC24H28Cl2FN3O2
SMILESCC=1C(C2=CC(OC)=C(F)C(OC)=C2)=CN=CC1C3=CC=C(C=C3)N4CCNCC4.Cl
TargetTGF-beta/Smad,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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M4K2163 dihydrochloride (orb2283336)

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