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Phleomycin E

SKU: orb3024661

Description

Phleomycin E is a peptide-based antibiotic that is effective against Gram-positive and Gram-negative bacteria as well as mycobacteria. It extends the survival time of mice with transplanted Ehrlich ascites carcinoma and shows inhibitory effects on murine pulmonary solid tumors, with an IC50 of 0.31 μg/mL.

Images & Validation

Key Properties

CAS Number11031-13-3
MW1540.68
FormulaC60H97N23O21S2
SMILESO=C(OC1C(O)C(OC(CO)C1O)OC2C(OC(C3=CN=CN3)C(NC(=O)C4=NC(=NC(N)=C4C)C(NCC(N)C(=O)N)CC(=O)N)C(=O)NC(C)C(O)C(C(=O)NC(C(=O)NCCC5=NC(C6=NC(=CS6)C(=O)NCCCCNC(=N)NCCCCNC(=N)N)CS5)C(O)C)C)OC(CO)C(O)C2O)N
TargetAntibacterial,Antibiotic

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Phleomycin E (orb3024661)

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