Phrixotoxin 3 TFA

SKU: orb1981599

Description

Phrixotoxin 3 TFA is a potent inhibitor of voltage-gated sodium channels, with IC50 values of 0.6 nM for NaV1.2, 42 nM for NaV1.3, 72 nM for NaV1.4, 288 nM for NaV1.1, and 610 nM for NaV1.5. This compound modulates the activity of these channels similarly to traditional gating-modifier toxins, inducing a depolarizing shift in gating kinetics and obstructing the inward sodium current.

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Key Properties

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MW	4173.74
Formula	C₁₇₈H₂₇₀F₃N₅₁O₅₀S₆
Target	Sodium Channel

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Sodium Channel

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