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PKM2-IN-8

SKU: orb2945714

Description

PKM2-IN-8 (Compound 9b) is a potent pyruvate kinase M2 (PKM2) inhibitor (IC50 = 0.31 µM) with antiproliferative effects in U87MG glioma cells. It induces apoptosis, reduces lactate production, and serves as a valuable research tool for studying glioblastoma metabolism in vitro.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

MW355.353
FormulaC19H13N7O
SMILESC1=CC=C2C=C(C=CC2=C1)C3=NN(N=N3)CC(=O)C4=CN=C5N4C=CC=N5
TargetApoptosis,PKM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

PKM2-IN-8 (orb2945714)

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