PROTAC BRD4 Degrader-27

SKU: orb2663678

Description

PROTAC BRD4 Degrader-27 is a selective PROTAC targeting BRD4, distinguished from BRD2/BRD3. This compound is composed of the E3 ubiquitinase ligand Thalidomide-4-OH, the PROTAC Linker γ-Aminobutyric acid, and the PROTAC target protein ligand PROTAC BRD4 ligand-3. The active control for this target protein ligand is Mivebresib, while the conjugate of the E3 ubiquitin ligase ligand and Linker is identified as Pomalidomide 4'-alkylC3-acid.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2407163-44-2
MW	708.67
Formula	C₃₇H₃₀F₂N₆O₇
SMILES	O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCC(=O)NC=4C=CC(OC5=CC=C(F)C=C5F)=C(C4)C6=CN(C(=O)C=7NC=CC67)C)C3C2=O)CC1
Target	PROTACs,Epigenetic Reader Domain

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

PROTACs,Epigenetic Reader Domain

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