Cart summary

You have no items in your shopping cart.

Serpinin

SKU: orb2563719

Description

Serpinin, an agonist of the protease inhibitor Nexin-1 (PN-1), upregulates PN-1 expression via the cAMP-PKA-Sp1 signaling pathway, facilitating granule biogenesis in endocrine cells. It is employed in research on secretory function regulation. Serpinin selectively targets β-adrenergic receptors, particularly interacting with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, thereby regulating myocardial systolic and diastolic function. Additionally, pGlu-serpinin upregulates Bcl2 mRNA transcription and provides neuroprotective effects.

Images & Validation

Key Properties

CAS Number1383743-23-4
MW2891.14
FormulaC125H204N32O46
SMILES[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]2CCCN2)CCC(O)=O)=O)CC(O)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CO)=O)CC(C)C)=O)CO)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCCN)=O)C(C)C)=O)C)=O

Storage & Handling

Storage-20°C
DisclaimerFor research use only

Similar Products

  • Chromogranin A CHGA Rabbit Monoclonal Antibody [orb547683]

    FC,  ICC,  IF,  IHC,  WB

    Human

    Rabbit

    Monoclonal

    Unconjugated

    100 μl
  • FHL1 Monoclonal Antibody [orb547684]

    IHC,  IP,  WB

    Human, Mouse, Rat

    Rabbit

    Monoclonal

    Unconjugated

    100 μl
  • Complement factor B Rabbit Monoclonal Antibody [orb866660]

    WB

    Human

    Rabbit

    Monoclonal

    Unconjugated

  • Recombinant Human CHGA Protein, N-His [orb2964760]

    >90% as determined by SDS-PAGE.

    50.33 kDa

    1 mg, 100 μg, 50 μg
  • CHGA Antibody [orb736732]

    IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    1 ml, 3 ml, 10 ml, 6 ml
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Serpinin (orb2563719)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%