Sigma-2 Radioligand 1

SKU: orb2565292

Description

Sigma-2 Radioligand 1 (compound 1) serves as a selective Sigma-2 ligand, demonstrating favorable biodistribution in mice and robust in vivo activity in rats. The [18F] modified version of Sigma-2 Radioligand 1 enhances the visualization of tumors in micro-PET/CT imaging by providing high tumor uptake and an impressive tumor-to-background ratio. Additionally, experiments confirm that this compound binds with high specificity to U87MG glioma xenografts.

Images & Validation

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Key Properties

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CAS Number	2860554-32-9
MW	427.51
Formula	C₂₄H₃₀FN₃O₃
SMILES	C(CCCN1CC=2C(CC1)=CC(OC)=C(OC)C2)N3C=4C(N(CCF)C3=O)=CC=CC4
Target	Sigma receptor

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Sigma receptor

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