3,4,5-Tricaffeoylquinic acid

SKU: orb1684871

Description

This research compound, 3,4,5-Tricaffeoylquinic acid, suppresses TLR4 expression to inhibit Akt, ERK, and NF-κB pathway activation, thereby reducing TNF-α and LPS-induced inflammatory mediator production in keratinocytes. It is a useful tool for studying inflammatory skin disease mechanisms in both cellular and animal models.

Research Area

Cell Biology, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	86632-03-3
MW	678.59
Formula	C₃₄H₃₀O₁₅
SMILES	OC(=O)[C@@]1(O)C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H](C1)OC(=O)\C=C\c1ccc(O)c(O)c1
Target	TNF,HIV Protease,Akt,NF-κB

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

6440783 ↗

Key Properties

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No computed properties available.

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