4-Hydroxycanthin-6-one

SKU: orb3141531

Description

4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of Ailanthus altissima. Additionally, five other known compounds were identified. The structure of the new compound was established through analysis of physical and spectral data, and its absolute configuration was determined using electronic circular dichroism and quantum chemical calculations. These compounds exhibit significant inhibitory activity on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, indicating potential anti-inflammatory properties.

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Key Properties

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CAS Number	106941-27-9
MW	236.23
Formula	C₁₄H₈N₂O₂
SMILES	O=C1C=C(O)C2=NC=CC=3C4=CC=CC=C4N1C23
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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