5-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

SKU: orb3028950

Description

5-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione is a Thalidomide analog featuring a hydroxyl group, which serves as a versatile site for further derivatization. Thalidomide acts as an E3 ligase activator and facilitates the ubiquitination of specific proteins.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2589697-74-3
MW	288.255
Formula	C₁₄H₁₂N₂O₅
SMILES	O=C1C2=CC=C(O)C=C2C(=O)N1C3C(=O)N(C(=O)CC3)C
Target	Ligands for E3 Ligase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Ligands for E3 Ligase

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