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(5Z)-7-Oxo-Zeaenol

SKU: orb1710786

Description

5Z-7-Oxozeaenol (FR148083) is a potent, irreversible, and selective TAK1 inhibitor (IC50 = 8.1 nM) with additional activity against VEGF-R2 (IC50 = 52 nM). It is widely used as a chemical probe in research to investigate TGF-β and NF-κB signaling pathways in both cellular and animal models of inflammation and cancer.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number253863-19-3
MW362.4
Purity>98%
FormulaC19H22O7
SMILESCOc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O
TargetKinase
SolubilitySoluble in DMSO (up to 9 mg/ml) or in Ethanol (up to 3 mg/ml)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

LL-Z-1640-2
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Key Properties

No computed properties available.

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Protocol Information

(5Z)-7-Oxo-Zeaenol (orb1710786)

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1 mg
$ 230.00
5 mg
$ 580.00
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