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5Z-7-Oxozeaenol

SKU: orb1710786

Description

5Z-7-Oxozeaenol (FR148083) is a potent, irreversible, and selective TAK1 inhibitor (IC50 = 8.1 nM) with additional activity against VEGF-R2 (IC50 = 52 nM). It is widely used as a chemical probe in research to investigate TGF-β and NF-κB signaling pathways in both cellular and animal models of inflammation and cancer.

Research Area

Cardiovascular Research, Infectious Disease & Virology, Signal Transduction

Images & Validation

Key Properties

CAS Number253863-19-3
MW362.37
Purity99.00% (May vary between batches)
FormulaC19H22O7
SMILESCOc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O
TargetAntibiotic,Src,MAPK,VEGFR,MEK,PDGFR,FLT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • 5Z-7-Oxozeaenol [orb2655745]

    >98% (HPLC)

    253863-19-3

    362.37

    C19H22O7

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Key Properties

No computed properties available.

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5Z-7-Oxozeaenol (orb1710786)

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