7,8-Didehydrocimigenol

SKU: orb1683343

Description

7,8-Didehydrocimigenol is a research compound with potential applications in cardiovascular disease research, particularly atherosclerosis. It functions by upregulating PPAR-γ and suppressing TNF-α-induced NF-κB activity in endothelial cells, leading to the selective downregulation of VCAM-1 expression. This mechanism has been investigated in vitro for its anti-inflammatory effects on the endothelium.

Research Area

Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	150972-72-8
MW	486.693
Formula	C₃₀H₄₆O₅
SMILES	[H][C@]12[C@H](C)C[C@H]3O[C@@]1(O[C@@H]3C(C)(C)O)[C@H](O)[C@@]1(C)C3=CC[C@]4([H])[C@]5(C[C@@]35CC[C@]21C)CC[C@H](O)C4(C)C \|t:20\|
Target	PPAR,IκB/IKK,Akt,TNF,ERK,NF-κB

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

101577840 ↗

Key Properties

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No computed properties available.

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