8-hydroxy Efavirenz (Standard)

SKU: orb3141256

Description

8-hydroxy Efavirenz (Standard) is a reference standard for research and analysis in studies involving 8-hydroxy Efavirenz. 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

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Key Properties

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CAS Number	205754-33-2
MW	331.68
Formula	C₁₄H₉ClF₃NO₃
SMILES	Oc1cc(Cl)cc2c1NC(=O)O[C@]2(C#CC1CC1)C(F)(F)F
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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