Acyclovir sodium

SKU: orb1909509

Description

Acyclovir sodium is a nucleoside analog antiviral agent that potently inhibits the DNA polymerases of herpes simplex virus (HSV- and varicella-zoster virus (VZV). It is widely used in research for studying antiviral mechanisms and efficacy in both cellular and animal models of herpesvirus infections.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

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Key Properties

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CAS Number	69657-51-8
MW	247.19
Purity	99.89% (May vary between batches)
Formula	C₈H₁₀N₅NaO₃
SMILES	O=C1N=C(NC2=C1N=CN2COCC[O-])N.[Na+]
Target	DNA/RNA Synthesis,Antibiotic,Antibacterial,HSV,Apoptosis
Solubility	DMSO:Soluble

Bioactivity

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Target IC50	HSV2:0.86 μM\|HSV1:0.85 μM
In Vitro	Jurkat, U937, and K562 leukemia cells were treated with Acyclovir sodium (3-100 μM, 24-72 hours) to measure cell viability. Results: Acyclovir sodium reduced cell viability in a dose- and time-dependent manner. Read more...

Storage & Handling

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Storage	keep away from direct sunlight,store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Aciclovir sodium, Acycloguanosine sodium, Acyclovir sodium

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Compound Identifiers

PubChem CID

23665721 ↗

Key Properties

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No computed properties available.

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