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Aloxistatin

SKU: orb1223751

Description

An irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets; reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B.Other Indication Discontinued.

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Key Properties

CAS Number88321-09-9
MW342.4305
Purity>98% (HPLC)
FormulaC17H30N2O5
SMILESCCOC([C@@H]1[C@@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)O1)=O
TargetCathepsin
SolubilityDMSO: ≥ 23 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

E64 d | Loxistatin | Rexostatine

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Aloxistatin (orb1223751)

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Available Sizes

Select a size below

2 mg
$ 100.00
5 mg
$ 140.00
10 mg
$ 190.00
25 mg
$ 290.00
50 mg
$ 500.00
100 mg
$ 730.00
500 mg
$ 1,550.00