AmPEG6C2-Aur0131

SKU: orb1988751

Description

AmPEG6C2-Aur0131 is a non-cleavable drug-linker conjugate for constructing anti-CXCR4 antibody-drug conjugates (ADCs). It delivers the auristatin-based payload Aur0131, a microtubule inhibitor, to target cells. This conjugate has demonstrated potent antitumor activity in both in vitro and in vivo cancer research models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1650569-94-0
MW	1065.34
Formula	C₅₄H₉₂N₆O₁₅
SMILES	[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC(=O)[C@@]3(C)N(C(CCOCCOCCOCCOCCOCCOCCN)=O)CCC3)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Target	Microtubule Associated,PROTAC Linker,Drug-Linker Conjugates for ADC

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

118480237 ↗

Key Properties

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No computed properties available.

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