Anti-inflammatory agent 42

SKU: orb1982248

Description

Anti-inflammatory agent 42 is a small molecule compound that demonstrates anti-inflammatory properties by suppressing TNF-α and IL-6 production in LPS-activated macrophages. It is a useful research tool for studying inflammatory pathways in cellular models and has shown activity in preclinical models of inflammation.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	877468-30-9
MW	328.39
Purity	98.13%
Formula	C₂₀H₁₂N₂OS
SMILES	O=C1N2C(S\C1=C/C1=C3C=CC=CC3=CC=C1)=NC1=C2C=CC=C1
Target	Interleukin,TNF,IL Receptor
Solubility	DMSO:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

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In Vitro	The anti-inflammatory agent 42 (Compound 10j; 10 μM; 2 h) inhibits TNF-α and IL-6 secretion in LPS-induced RAW 264.7 macrophages.

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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IL Receptor, IL-6, ILReceptor, TNF-α

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Compound Identifiers

PubChem CID

825616 ↗

Key Properties

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No computed properties available.

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