Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Antileukinate

SKU: orb1693580

Description

Antileukinate is an acetylated, amidated hexapeptide antagonist of the CXCR2 chemokine receptor. It blocks IL-8 binding and neutrophil activation in vitro (Ki = 2.7-13 μM) and demonstrates protective effects in vivo, such as reducing acute pancreatitis and associated lung injury in mouse models at 53 mg/kg.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetCXCR
CAS Number138559-60-1
MW1003.19
FormulaC45H66N18O7S
SMILESC([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CS)=O)=O)NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)CCCNC(=N)N)=O)C=3C=4C(NC3)=CC=CC4

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • IL-8 Inhibitor [orb2694092]

    ≥95%

    1003.2

    5 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide

Antileukinate (orb1693580)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet