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Antileukinate

SKU: orb1693580

Description

Antileukinate is an acetylated, amidated hexapeptide antagonist of the CXCR2 chemokine receptor. It blocks IL-8 binding and neutrophil activation in vitro (Ki = 2.7-13 μM) and demonstrates protective effects in vivo, such as reducing acute pancreatitis and associated lung injury in mouse models at 53 mg/kg.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetCXCR
Molecular Weight1003.19

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Antileukinate (orb1693580)

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