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APL-1092

SKU: orb2802326

Description

APL-1092 (Mal-Exo-EEVC-Exatecan) is a drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs). It incorporates the potent topoisomerase I inhibitor Exatecan, enabling targeted delivery for cancer research. This conjugate is applied in both in vitro cytotoxicity assays and in vivo efficacy studies of ADC candidates.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2921735-91-1
MW1349.37
FormulaC65H77FN12O19
SMILESN(C(OC(C(NCCCCCN1C(=O)C=CC1=O)=O)C2=CC=C(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(C)=O)=O)CCC(O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C2)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
TargetTRP/TRPV Channel,Endogenous Metabolite,Drug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

APL-1092 (orb2802326)

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