(Arg)9 TFA (143413-47-2 free base)

SKU: orb1296761

Description

Images & Validation

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Key Properties

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CAS Number	2283335-13-5
MW	1537.71
Purity	100.00%
Formula	C₅₆H₁₁₁F₃N₃₆O₁₂
SMILES	C(C(O)=O)(F)(F)F.[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N
Target	Others
Solubility	H2O:10 mM;DMSO:Insoluble

Bioactivity

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Target IC50

Neuroprotection:0.78 μM IC50

In Vivo

(Arg)9) (D-isoform) is neur Protective in rat stroke models. (Arg)9) is highly neuroprotective, with efficacy increasing with increasing arginine content. It ha the capacity to reduce glutamic acid-induced neuronal calcium influx and requires heparan sulfate preotoglycan-mediated endocytosis to induce a neur Protective effec. (Arg)9) (D-isoform) administered intravenously at a dose of 1000 nM L/kg 30 min after permanent middle cerebral artery occlusion (MCAO) reduces infarct volum.

Storage & Handling

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Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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143413-47-2, 143413-47-2 free base, (Arg)9, (Arg)9 TFA, (Arg)9 TFA (143413 47 2 free base), (Arg)9 TFA (143413472 free base), neuroprotection, inhibit, Nona-L-arginine (TFA), Nona-L-arginine, Inhibitor, Peptide R9, Peptide R-9, Peptide R9 (TFA), Peptide R 9

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Compound Identifiers

PubChem CID

145707711 ↗

Key Properties

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No computed properties available.

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