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ASN04885796

SKU: orb1698319

Description

ASN04885796 (compound IV) is a potent and selective GPR17 agonist, exhibiting an EC50 of 2.27 nM in GTPγS binding assays. This neuroprotective agent is a valuable research tool for investigating pathological mechanisms and potential treatments for cerebral ischemia and demyelinating disorders in both cellular and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1032892-26-4
MW517.55
Purity95.36% (May vary between batches)
FormulaC28H28FN5O4
SMILESO=C(NCC1OCCC1)C(C2=CC=C(F)C=C2)N(C(=O)CN3N=NC=4C=CC=CC43)C5=CC=C(OC)C=C5
TargetGPCR,Others
SolubilityDMSO:80 mg/mL (154.57 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (6.38 mM)

Bioactivity

Target IC50
GTPγS binding assay:2.27 nM (EC₅₀)
In Vitro
ASN04885796 (compound IV) is a potent GPR17 agonist, exhibiting an EC₅₀ of 2.27 nM in assays measuring GTPγS binding stimulated by GPR17. ASN04885796 possesses neuroprotective effects and serves as a valuable tool for studying neurological disorders.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AS N 04885796, AS N04885796, AS N-04885796, ASN04885796, AS-N04885796, AS-N-04885796, ASN-04885796, ASN 04885796, AS-N 04885796
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

ASN04885796 (orb1698319)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 190.00
1 ml x 10 mM (in DMSO)
$ 210.00
10 mg
$ 280.00
25 mg
$ 440.00
50 mg
$ 630.00
100 mg
$ 880.00
200 mg
$ 1,170.00
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