Atorvastatin hemicalcium trihydrate

SKU: orb1745132

Description

Atorvastatin Hemicalcium Trihydrate is an orally active lipid-lowering agent that potently inhibits HMG-CoA reductase. It also suppresses the proliferation and invasion of human vascular smooth muscle cells (SV-SMC) in vitro, with IC50 values of 0.39 μM and 2.39 μM, respectively. This compound is widely used in cardiovascular disease research, including studies on atherosclerosis and restenosis in both cellular and animal models.

Research Area

Cell Biology, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	344920-08-7
MW	632.73
Formula	C₃₃H₃₅FN₂O₅.1/2Ca.3H₂O
SMILES	O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.O=C(C5=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C6=CC=C(C=C6)F)=C5C7=CC=CC=C7)NC8=CC=CC=C8.[Ca+2].O.O.O.O.O.O
Target	Others,HMG-CoA Reductase,Autophagy

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

168440556 ↗

Key Properties

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No computed properties available.

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