Avizakimab Antibody

SKU: orb1980530

Description

Avizakimab (BOS161721) is a humanized monoclonal antibody designed to neutralize interleukin-21 (IL-21) activity. It is a research tool for investigating IL-21's role in autoimmune pathologies, particularly systemic lupus erythematosus (SLE), and is utilized in both in vitro cellular assays and in vivo preclinical studies.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	2229685-51-0
MW	145.12 kDa
Purity	95.00%
Target	Interleukin

Bioactivity

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In Vitro	In vitro, Avizakimab blocks IL-22 binding to IL-22R1 and inhibits downstream STAT3 phosphorylation.

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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BOS 161721, BOS161721

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Quick Database Links

Gene Symbol

Interleukin

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