Cart summary

You have no items in your shopping cart.

BVT 2733

SKU: orb1306609

Description

BVT 2733 is a selective, non-steroidal small molecule inhibitor targeting the 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme. It is utilized in metabolic disease research, including studies on obesity and diabetes, for both in vitro enzymatic assays and in vivo models to investigate glucocorticoid regulation.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number376640-41-4
MW428.96
Purity99.64% (May vary between batches)
FormulaC17H21ClN4O3S2
SMILESCN1CCN(CC1)C(=O)Cc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1
TargetDehydrogenase
SolubilityDMSO:60 mg/mL (139.87 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM)

Bioactivity

Target IC50
11β-HSD1 (mouse):96 nM (IC50)|11β-HSD1 (human):3341 nM (IC50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

disease, collagen, CIA, adipocyte, 11β-HSD1, arthritis, BVT 2733, BVT2733, BVT-2733, macrophage, obesity, inhibit, J774.1, Inhibitor, HFD

Similar Products

  • BVT-2733 hydrochloride [orb2814110]

    376641-65-5

    465.42

    C17H22Cl2N4O3S2

    50 mg, 10 mg
  • BVT-2733 [orb1225161]

    >98% (HPLC)

    376640-41-4

    428.9566

    C17H21ClN4O3S2

    1 g, 10 mg, 25 mg, 100 mg, 50 mg, 2 mg, 5 mg, 500 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

BVT 2733 (orb1306609)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 80.00
5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 170.00
50 mg
$ 260.00
100 mg
$ 370.00
200 mg
$ 510.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry