Camidanlumab tesirine Antibody

SKU: orb3031958

Description

Camidanlumab tesirine (ADCT 301) is an ADC consisting of a human IgG1 antibody, HuMax-TAC, targeting CD25, which is conjugated through a dipeptide-cleavable linker to pyrrolobenzodiazepine (PBD) dimer payloads. The drug-antibody ratio (DAR) of Camidanlumab tesirine is 2.3. It binds to human CD25 with picomolar affinity and exhibits potent and selective cytotoxicity against human lymphoma cell lines expressing CD25.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Recombinant
Target	Antibody-Drug Conjugates (ADCs),Interleukin
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Antibody-Drug Conjugates (ADCs),Interleukin

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