Canine COL6A6 Protein, His Tag

SKU: orb3158251

Description

COL6A6 belongs to the type VI collagen family and is an extracellular matrix component highly expressed in the lungs, adipose tissue, and skeletal muscle. It provides structural support and regulates signaling by inhibiting the PI3K-Akt pathway to play a tumor-suppressive role. Its abnormalities are closely linked to skin inflammation, retinitis pigmentosa, and pituitary adenoma, making it a potential diagnostic marker or therapeutic target.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 62.8 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	COL6A6
Reactivity	Canine
Tag	N-10×His
Molecular Weight	62.8 kDa
Expression Region	Asp 437 - Val 983
Purity	90%
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

COL6A6

RefSeq:A0A8C0PIB6

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	A0A8C0PIB6

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