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cis-J-113863

SKU: orb2283355

Description

Cis-J-113863 is a potent and selective competitive antagonist of the chemokine receptor CCR1, exhibiting IC50 values of 0.9 nM (human) and 5.8 nM (mouse). It is a valuable research tool for studying CCR1-mediated inflammatory and autoimmune pathways in both cellular assays and animal disease models.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number202796-41-6
MW655.44
FormulaC30H37Cl2IN2O2
SMILESC(N[C@@H]1CC[N@@+](CC=2CCCCCCC2)(CC)CC1)(=O)C3C=4C(OC=5C3=CC(Cl)=CC5)=CC=C(Cl)C4.[I-]
TargetOthers,CCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

cis-J-113863 (orb2283355)

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