Cart summary

You have no items in your shopping cart.

Cleomiscosin A

SKU: orb1297420

Description

Cleomiscosin A, isolated from Acer okamotoanum, is a bioactive compound that inhibits TNF-α secretion in mouse peritoneal macrophages. It serves as a research tool for studying anti-inflammatory mechanisms and the prevention of LDL oxidation, relevant to atherosclerosis research in both in vitro and in vivo models.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number76948-72-6
MW386.35
Purity>99.99% (May vary between batches)
FormulaC20H18O8
SMILESCOc1cc(ccc1O)[C@H]1Oc2c(OC)cc3ccc(=O)oc3c2O[C@@H]1CO
TargetLDL,Antioxidant,TNF
SolubilityDMSO:1.9 mg/mL (4.92 mM)

Bioactivity

In Vitro
Cleomiscosin A protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl with IC50s of 13.4 and 8.1 μM, respectively.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TNF-α, LDL, Antioxidant, Cleomiscosin A

Similar Products

  • Cleomiscosin C [orb1682926]

    84575-10-0

    416.38

    C21H20O9

    1 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Cleomiscosin A (orb1297420)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 170.00
10 mg
$ 240.00
25 mg
$ 400.00
50 mg
$ 540.00
100 mg
$ 720.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry