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CPX-351

SKU: orb1697662

Description

CPX-351 (Vyxeos) is a liposomal formulation co-encapsulating cytarabine and daunorubicin, designed for synergistic antitumor activity. It is widely used in acute myeloid leukemia (AML) research, with applications in both in vitro cytotoxicity assays and in vivo xenograft model studies to evaluate its efficacy and mechanism of action.

Images & Validation

Key Properties

CAS Number1256639-86-7
MW770.74
Purity98.95% (May vary between batches)
FormulaC36H42N4O15
SMILESO[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2.OC=1C2=C([C@@H](O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C[C@@](C(C)=O)(O)C2)C(O)=C4C1C(=O)C=5C(C4=O)=C(OC)C=CC5
TargetOthers

Bioactivity

Target IC50
Cyt:Daun:0.03:0.006 uM to 10:2 uM|Primary AML cells、leukemia blast cells:0.223 µM|NMUR1:45 nM (Kb)|NMUR1:7.35 (pA2)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CPX351, CPX-351, CPX 351, Daunonubicin/cytarabine, Cytarabine/daunonubicin, Vyxeos
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

CPX-351 (orb1697662)

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% DMSO +
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% Tween 80 +
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1 mg
$ 1,310.00
5 mg
$ 2,590.00
DispatchUsually dispatched over 10 weeks
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