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Desmethoxy yangonin

SKU: orb1222650

Description

Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism.

Images & Validation

Key Properties

CAS Number15345-89-8
MW228.24
Purity>98% (HPLC)
FormulaC14H12O3
SMILESCOC1=CC(=O)OC(=C1)C=CC2=CC=CC=C2
TargetOthers
SolubilityIn Vitro: DMSO : 14.29 mg/mL (62.61 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Demethoxyyangonin | 5,6-Dehydrokavain

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Protocol Information

Desmethoxy yangonin (orb1222650)

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100 mg
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5 mg
$ 210.00
10 mg
$ 290.00
25 mg
$ 480.00
50 mg
$ 690.00