Dolutegravir intermediate-1

SKU: orb1218922

Description

Dolutegravir intermediate-1 is a new synthetic Dolutegravir intermediate extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.

Images & Validation

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Key Properties

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CAS Number	1335210-23-5
MW	314.27
Purity	>98% (HPLC)
Formula	C₁₃H₁₆NO₈
SMILES	COC(CN(C=C(C([O-])=O)C1=O)C(C(OC)=O)=C1OC)OC
Target	HIV
Solubility	DMSO: 100 mg/mL (285.46 mM; Need ultrasonic)

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid | 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid

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Gene Symbol

HIV

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