FSLLRY-NH2 TFA(245329-02-6 free base)

SKU: orb1296451

Description

FSLLRY-NH2 TFA is a selective protease-activated receptor 2 (PAR2) antagonist. It has demonstrated efficacy in vivo by alleviating taxol-induced neuropathic pain and itch in mouse models. In vitro, it inhibits PAR2-mediated signaling, blocking ERK activation and collagen production in cardiac fibroblasts.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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Target	Protease-activated Receptor
Molecular Weight	910.99
Purity	99.32% (May vary between batches)
Formula	C₄₁H₆₁F₃N₁₀O₁₀
SMILES	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CC=CC=C2)N.O=C(O)C(F)(F)F

Storage & Handling

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Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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PAR2, FSLLRY NH2 TFA(245329 02 6 free base), FSLLRYNH2 TFA(245329026 free base), FSLLRY-NH-2 TFA(245329-02-6 free base), FSLLRY-NH2 TFA(245329-02-6 free base), Proteaseactivated Receptor, ProteaseactivatedReceptor

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Compound Identifiers

PubChem CID

155977585 ↗

Key Properties

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No computed properties available.

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