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Fudosteine

SKU: orb1226549

Description

Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor. (In Vitro):Fudosteine (50, 100, 200 mg/kg) decreases the LPS-induced p-ERK1/2 and p-p38 MAPK levels in the rat lungs. The TNF-α-induced increase in MUC5AC mRNA expression is inhibited by pretreatment with 1 mM Fudosteine.

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Key Properties

CAS Number13189-98-5
MW179.23
Purity>98% (HPLC)
FormulaC6H13NO3S
SMILESN[C@@H](CSCCCO)C(O)=O
TargetMUC5AC mucin
SolubilityWater: 36 mg/mL (200.84 mM)

Bioactivity

In Vitro
Fudosteine (50, 100, 200 mg/kg) decreases the LPS-induced p-ERK1/2 and p-p38 MAPK levels in the rat lungs. The TNF-α-induced increase in MUC5AC mRNA expression is inhibited by pretreatment with 1 mM Fudosteine.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SS320A

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Fudosteine (orb1226549)

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500 mg
25 mg
$ 100.00
50 mg
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100 mg
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200 mg
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