G-quadruplex ligand 4

SKU: orb3175179

Description

G-quadruplexligand 4, a chromone derivative, functions as a human telomerase reverse transcriptase (hTERT) G4 ligand. It downregulates hTERT expression and exhibits significant cytotoxicity in triple-negative breast cancer (TNBC) cell lines. This compound induces S/G2 phase cell cycle arrest and apoptosis, while also downregulating the expression of hTERT, KRAS, and BCL-2. G-quadruplexligand 4 is utilized in research related to triple-negative breast cancer.

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Key Properties

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Target	Bcl-2 Family,Apoptosis,Telomerase,DNA/RNA Synthesis,Ras

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Bcl-2 Family,Apoptosis,Telomerase,DNA/RNA Synthesis,Ras

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