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(-)-Gallocatechin gallate

SKU: orb1222273

Description

(-)-Gallocatechol gallate is an HIV integrase inhibitor found in Camilla sinensis. It displays a wide variety of biological activities, including suppressing amyloid formation by islet amyloid polypeptide, preventing nematode hatching, and inhibiting osteoclast differentiation.

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Key Properties

CAS Number4233-96-9
MW458.38
Purity>98% (HPLC)
FormulaC22H18O11
SMILESC1[C@H]([C@@H](Oc2cc(cc(c12)O)O)c1cc(c(c(c1)O)O)O)OC(=O)c1cc(c(c(c1)O)O)O
TargetAntibacterial
SolubilityDMSO : ≥ 150 mg/mL; 327.25 mM

Bioactivity

In Vitro
The amount of (-)-Gallocatechin gallate does not differ in leaves of different stages, and the content is relatively low. (-)-gallocatechin gallate in combination with active catechins ((-)-epigallocatechin gallate) has synergistic effects on the induction of apoptosis and inhibition of cell growth for PC-9 cells. (-)-gallocatechin gallate shows inhibitory effect on α-Glucosidase and DPPH, with IC50s of 30.2 μM and 12.2 μg/mL.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(-)-Gallocatechol gallate | CCRIS 9286

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(-)-Gallocatechin gallate (orb1222273)

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200 mg
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$ 80.00
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$ 160.00
25 mg
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50 mg
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100 mg
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