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GS-443902

SKU: orb1984329

Description

Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number1355149-45-9
MW531.2
FormulaC12H16N5O13P3
SMILESNc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N
TargetDrug Metabolite,DNA/RNA Synthesis,RSV,SARS-CoV,HCV Protease,Nucleoside Antimetabolite/Analog

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

GS-443902 (orb1984329)

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